第六届TICPS国际蛋白质科学会议暨全国结构生物学会议_

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第六届TICPS国际蛋白质科学会议暨全国结构生物学会议

会议日期：2009-11-9 至 2009-11-11

会议地点：上海市

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会议简介

Morning Session on Nov. 9^th

*8:00 – 9:00*	*On-site Registration in SIBS*
09:00 – 10:15	Opening ceremony & conference photo Chair: Dr. Jianping Ding
	Presentations by invited speakers Chair: Dr. Timothy A. Springer
10:15 – 10:50	Symmetry and asymmetry in the life cycle of viruses Name: Michael G. Rossmann Institution: Purdue University, USA
10:50 – 11:25	HIV reverse transcriptase: high resolution crystal engineering, inhibitor strategic flexibility, and fragment screening Name: Eddy Arnold Institution: CABM and Rutgers University, USA
11:25 – 12:00	Insights into elegantly programmed nanomachines: Biophysical analysis of virus particles and their maturation Name: Jack Johnson Institution: The Scripps Research Institute, USA
*12:00 – 13:30*	*Lunch / Lunchtime seminars by Rigaku and Pfizer ( pizza, drink & gifts provided）*

Afternoon Session on Nov. 9^th

	Presentations by invited speakers Chair: Dr. Yigong Shi
13:30 – 14:05	Architecture of cyanobacterial photosystem II at 3 Å resolution: perspectives, conclusions and outlook Name: Wolfram Saenger Institution: Freie Universitat Berlin, Germany
14:05 – 14:40	Structures of cytochrome bc1 complexes and their functional implications Name: Di Xia Institution: National Institutes of Health, USA
14:40 – 15:15	Epigenetic link between DNA methylation and histone modifications Name: Xiaodong Cheng Institution: Emory University, USA
*15:15 – 15:45*	*Coffee break*
	Presentations by invited speakers Chair: Dr. Xiaodong Cheng
15:45 – 16:20	Ultraconserved nonsense: pervasive unproductive splicing of SR proteins associated with ultraconserved DNA elements Name: Steven E. Brenner Institution: University of California at Berkeley, USA
16:20 – 16:55	Structural Mechanisms of Transcriptional Silencing Name: Rui-Ming Xu Institution: New York University, USA
16:55 – 17:30	The mechanism of ribonuclease III action: how dicer dices Name: Xin-Hua Ji Institution: National Institutes of Health, USA
18:00– 19:00	*Rigaku: Reception (at Hope Hotel)*
19:00– 20:20	*Seminar by some of the sponsors (gifts provided)*
20:30– 21:30	Special session – - How to apply for a postdoctoral position overseas by Dr. Steven Brenner - Early career development in the academia by Dr. Yigong Shi - Early career development in the industry by Dr. Yuanhua Ding

Conference Program

Morning Session on Nov. 10^th

	Presentations by invited speakers Chair: Dr. Steven E. Brenner
08:30 – 09:05	Conformational change and ligand binding in integrins Name: Timothy A. Springer Institution: Harvard University, USA
09:05 –09:40	Structural Insights into Regulated Intramembrane Proteolysis Name: Yigong Shi Institution: Princeton University, USA
09:40 –10:15	Structure and function studies of serum amyloid P component recognition by Fcγ receptors Name: Peter D. Sun Institution: National Institutes of Health, USA
*10:15 – 10:45*	*Coffee break*
	Presentations by invited speakers Chair: Dr. Eddy Arnold
10:45 – 11:20	Exploring Biological and Chemical Space with High-throughput Crystallography: The New Dimensions of Drug Discovery Name: Tom Blundell Institution: University of Cambridge, UK
11:20 – 11:40	Building an integrated structural biology platform to address challenges in drug discovery Name: Yuanhua Ding Institution: Pfizer, USA
11:40 – 11:55	The PDB as a resource for modern biological research Name: Zukang Feng Institution: RCSB PDB, Rutgers University, USA
*12:00 – 13:30*	*Lunch / Lunchtime seminars by GE Healthcare and TTP LabTech ( pizza, drink & gifts provided）*

Afternoon Session on Nov. 10^th

	Presentations by invited speakers Chair: Dr. Rui-Ming Xu
13:30 – 14:05	Structural aspects of SNARE - botulinum neurotoxin interactions Name: Axel Brünger Institution: Stanford University, USA
14:05 – 14:40	Structure and function of human proteins in cell junction Name: Yunyu Shi Institution: University of Science of Technology of China, China
14:40 – 15:15	Structural studies of fatty acid metabolism and relevance to the obesity epidemic Name: Liang Tong Institution: Columbia University, USA
15:15 – 15:50	Synchrotron-Based Structural Proteomics of Vesicle Transport: Rab Activation and Effector Interaction, and Ubiquitin Recognition Name: Soichi Wakatsuki Institution: Photon Factory and Structural Biology Research Center，KEK, Japan
15:50 –18:30	Poster presentations
*19:00-21:00*	*Pfizer:* *Conference banquet & award announcement (at Pearl Restaurant)*

Conference Program

Morning Session on Nov. 11^th

	Presentations by plenary session speakers Chair: Yuequan Shen
09:00 – 09:35	Structure of human synbindin reveals two conformations and a novel binding region in its PDZ-like domain Name: Weiming Gong Institution: Institute of Biophysics, CAS
09:35 –10:10	Multifunctional transcriptional co-activator p100 is involved in splicing: functional and structural basis Name: Zhi-jie Liu Institution: Institute of Biophysics, CAS
*10:10 – 10:40*	*Coffee break*
10:40 – 11:15	Functional roles of human MRG15 and its homologues in histone modification and transcription regulation Name: Jianping Ding Institution: Institute of Biochemistry and Cell Biology, SIBS, CAS
11:15 – 11:50	Functional Protein Design Targeting Protein-Protein Interface Name: Luhua Lai Institution: Peking University
*12:00 – 13:30*	*Lunch*

Afternoon Session on Nov. 11^th

	Presentations by plenary session speakers Chair: Weiming Gong
13:30 – 14:05	Analysis from the Tissue Specificity to Function Enrichment by MiRNA Microarray Name: Yixue Li Institution: Shanghai Institutes for Biological Sciences, CAS
14:05 – 14:40	Target Identification Using Small Molecules as Probes Name: Hualiang Jiang Institution: Shanghai Institute of Materia Medica, CAS
14:40 – 15:15	Solving Enzyme Structures by Metabolic Pathways Name: Xiaodong Su Institution: Peking University
*15:15 – 15:45*	*Coffee break*
15:45 – 16:20	How does one receptor accommodate two ligands? Crystal structure of urokinase receptor in complex with urokinase and vitronectin Name: Mingdong Huang Institution: Fujian Institute of Research on the Structure of Matter, CAS and Harvard University, USA
16:20 –16:55	Protein structures and functions studied via synchrotron radiation methods Name: Yuhui Dong Institution: Institute of High Energy Physics, CAS
16:55 –17:30	Insulin-degrading enzyme Name: Yuequan Shen Institution: Nankai University
*18:30-20:30*	*Dinner at Hongqiao Restaurant*